Currently browsing posts about: Fruit

I learned about this one from a press release: “Can eating mangoes reduce women’s facial wrinkles?”

A new study from researchers at the University of California, Davis, finds eating Ataulfo mangoes, also known as honey or Champagne mangoes, may have another benefit — reducing facial wrinkles in older women with fairer skin. The study was published in the journal Nutrients.

Postmenopausal women who ate a half cup of Ataulfo mangoes four times a week saw a 23 percent decrease in deep wrinkles after two months and a 20 percent decrease after four months.

Surely, this can’t be serious?  Who paid for this?

The study: Prospective Evaluation of Mango Fruit Intake on Facial Wrinkles and Erythema in Postmenopausal Women: A Randomized Clinical Pilot Study.  Vivien W. Fam, Roberta R. Holt Carl L. Keen, Raja K. Sivamani .  and Robert M. Hackman.  Nutrients 2020, 12(11), 3381; https://doi.org/10.3390/nu12113381

Method: Women were given either 85 g or 250 g of mangos to eat every day for 16 weeks.  Their wrinkles were photographed and measured before and after.

Conclusion: “The intake of 85 g of mangos reduced wrinkles in fair-skinned postmenopausal women, while an intake of 250 g showed the opposite effect.”

Funding: “This study was supported in part by a grant from the National Mango Board (NMB)…which also supplied the fresh mangos for the study. The NMB had no role in the study design, data collection, data analysis, manuscript preparation, or publication decision.”

Conflicts of Interest: The authors declare no conflict of interest.

Comment:  I love mangos (despite being somewhat allergic to them), but come on.  According to the press release, the researchers “said it’s unclear why consuming more mango would increase the severity of wrinkles but speculate that it may be related to a robust amount of sugar in the larger portion of mangoes.”  Another interpretation is that mangos have no effect (which makes more sense).  In any case, this study did not compare mangos to any other fruit.  This is a classic case of an industry-sponsored study coming out with results favorable to the sponsor’s interests and allowing those interests to be announced in a press release.  The authors may think industry sponsorship does not create a conflict of interest, but much evidence strongly suggests that it does (I reviewed that evidence in my book, Unsavory Truth).

Thanks to Lisa Young for sending this announcement: New Research Examines Blueberries’ Positive Impact in Men with Type 2 Diabetes. 

I am already on record as saying that I love blueberries, but I wish they weren’t marketed as superfoods.  All fruits, vegetables, nuts, and grains provide nutrients and fiber.  That makes all of them worth eating for their nutrition-and-health value as well as their taste.  Singling out one or another makes no sense to me, but I’m not in the business of selling one rather than another.  Because similar results would be expected from studies of many other fruits, I put this one in the category of marketing research.

Effect of Blueberry Consumption on Cardiometabolic Health Parameters in Men with Type 2 Diabetes: An 8-Week, Double-Blind, Randomized, Placebo-Controlled Trial.  Kim S Stote, Margaret M Wilson, Deborah Hallenbeck, Krista Thomas, Joanne M Rourke, Marva I Sweeney, Katherine T Gottschall-Pass, Aidar R Gosmanov.  Current Developments in Nutrition, Volume 4, Issue 4, April 2020, nzaa030. 

Conclusion: “Consumption of 22 g freeze-dried blueberries for 8 wk may beneficially affect cardiometabolic health parameters in men with type 2 diabetes.”

Funding:  “Supported by the US Highbush Blueberry Council (to KSS, MMW, and ARG) and by resources and the use of facilities at the Stratton VA Medical Center, Albany, NY, USA.  Author disclosures: KSS, MMW, and ARG received intervention products from the US Highbush Blueberry Council. All other authors report no conflicts of interest.  The US Highbush Blueberry Council supplied the funds to conduct the study but was not involved in the design, implementation, analysis, or interpretation of data.

Comment:  The funder does not have to be involved.  Everyone knows funders are not interested in funding research that might produce results unfavorable to their product.  Freeze-dried blueberries sound like medicine.  I’d rather eat the real things.

For no particular reason other than curiosity, I’ve been hanging on to these items.  This feels like a good time to share them.

• Thorny issue: Malaysian durian industry hit by demand slump and manpower shortage due to COVID-19:  The durian industry in Malaysia has been hit hard by a drastic drop in demand and lack of manpower due to the COVID-19 outbreak, a sharp downturn for one of the country’s most popular exports.  Read more
• Wake up and smell the … peanuts? Virginia Gold Peanut Coffee offers novel twist on classic drink:  With the invention of peanut coffee, fifth generation peanut farmer James Harrell found a way to combine in one product the rich history and future of his hometown of Suffolk, Va., which as the headquarters for Planters Peanuts was once known as the ‘peanut capital of the world’ before an influx of prominent coffee companies inspired the new moniker ‘caffeine capital.’… Read more
• The recipe for ‘healthier’ milk chocolate? Just add peanut waste:  Scientists claim to have found a ‘new way’ to boost the antioxidant properties of milk chocolate: by combining it with waste peanut skins…. Read more
• Apricot kernels recalled in New Zealand due to poisoning risk:   Raw apricot kernels are being recalled in New Zealand after three people needed hospital treatment. They were sold by Christchurch business Ethnic Market in Linwood. Sale of raw apricot kernels is prohibited under New Zealand food law. Those admitted to the hospital as a precaution have since been discharged after eating the raw kernels. Ethnic General… Continue Reading  
  What’s for dinner? Grasshoppers, says Hargol FoodTech as it raises $3m to build edible insect operationIsraeli firm Hargol FoodTech – which is blazing a distinct trail in the embryonic edible insect sector by focusing on grasshoppers, rather than crickets – has completed a $3m financing round from existing shareholders, Singapore-based Sirius Venture Capital and Netherlands-based SLJ Investment Partners…. Read more
• Insect fat the new butter replacement? Researchers see potential in bakery products: Researchers have examined the potential for black soldier fly larvae fat to partially substitute butter in cakes, cookies and waffles…. Read more 
  Farmed sea cucumbers: The new ‘superfood’ functional ingredient?  Researchers in Norway are investigating commercial farming practices for sea cucumbers, which they say should be exploited as a raw ingredient for health products…. Read more
• White paper: The fiber opportunity in dairy: Want to learn more about how to replace sugar with dietary fiber in dairy products without losing their sweetness? …Download our free paper to learn all you need to know about our biological solution Saphera® Fiber.  [this is an ad]

I learned about this one from Nutra-Ingredients-latam.com, one of those industry newsletters I avidly follow: “Grapes plus blueberries may boost cognitive function in college students.”

The study: Acute Intake of a Grape and Blueberry Polyphenol-Rich Extract Ameliorates Cognitive Performance in Healthy Young Adults During a Sustained Cognitive Effort.  Philip P, et al.  Antioxidants 2019, 8, 650; doi:10.3390/antiox8120650.

Purpose: “This study investigated the acute and sustained action of a polyphenols-rich extract from grape and
blueberry (PEGB), on working memory and attention in healthy students during a prolonged and intensive cognitive effort.”

The comparison: “Participants were asked to either consume 600 mg of polyphenol-rich active extract made from
grape (Vitis vinifera L.) and wild blueberry (Vaccinium angustifolium) (Memophenol, Activ’Inside, Beychac et Caillau, France), or a placebo containing pure maltodextrin (Maltrin® M100, Roquette, Lestrem, France) and providing no polyphenol.”

Conclusion: “Our findings suggest that consumption of PEGB coupled with a healthy lifestyle may be a safe alternative to acutely improve working memory and attention during a sustained cognitive effort.”

Funding: This study was funded by Activ’Inside (Bordeaux area, France).

Comment: All I had to do was see the title of this study to guess that it was funded by a company with a vested interest in the study’s outcome.  Activ’Inside makes antioxidant extracts for purposes like this.  I’m all for college students eating grapes and blueberries rather than taking drugs to keep them up all night, but flavanol extracts?  Not the same.  Chalk this one up to marketing, not science.

Every now and then a study comes out that I just love.

Two apples a day lower serum cholesterol and improve cardiometabolic biomarkers in mildly hypercholesterolemic adults: a randomized, controlled, crossover trial.

At last, scientific proof of what we’ve always been taught.

Well, two apples, but OK.

Also OK, who paid for this?

Supported in part by AGER (Agribusiness and research) grant no. 2010-2119 funding the project “Apple fruit quality in the post-genomic era, from breeding new genotypes to post-harvest: nutrition and health.”

AGER is an Italian foundation devoted to promoting Italian agribusiness, supported, it says, by banking foundations.

I’ll take that at face value and enjoy the research.

The study: Matthews LG, Smyser CD, Cherkerzian S, Alexopoulos D, Kenley J, Tuuli MG, et al. (2019) Maternal pomegranate juice intake and brain structure and function in infants with intrauterine growth restriction: A randomized controlled pilot study. PLoS ONE 14(8): e0219596.

The findings (my emphasis): “There were no group differences in brain injury, metrics or volumes. However, treatment subjects displayed reduced diffusivity within the anterior and posterior limbs of the internal capsule compared with placebo. Resting state functional connectivity demonstrated increased correlation and covariance within several networks in treatment subjects, with alterations most apparent in the visual network in per-protocol analyses. Direct effects on health were not found.

Conclusion: In conclusion, maternal pomegranate juice intake in pregnancies with known IUGR was associated with altered white matter organization and functional connectivity in the infant brain, suggesting differences in brain structure and function following in utero pomegranate juice exposure, warranting continued investigation.

Funding: This work was supported by National Institute of Health Grants R01 HD29190 (D. M. Nelson), K02 NS089852 (C.D. Smyser), U54 HD087011 and P30 HD062171 (T.E. Inder), The Foundation for Barnes-Jewish Hospital (D. M. Nelson) and an unrestricted gift to Washington University School of Medicine from POM Wonderful, Los Angeles, CA. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Comment: This is a classic example of interpretation bias.  Studies of bias associated with industry funding find that it shows up mostly in the framing of the research question or in the interpretation, as this one demonstrates.  The study did not find anything significant but concluded that drinking pomegranate juice during pregnancy is good for the growing fetus.

Bottom line: Fruit juices (of any kind) are good for health as long as volumes are small.  Eating the fruit itself is better–less sugar, more fiber.

I get letters like this from food trade associations all the time.  Here is the latest:.

The U.S. Highbush Blueberry Council has issued a request for research proposals (RFP) for which it offers grants ranging from $75,000 to $300,000 (or larger).

Here’s the get-go bias point (my emphasis):

The goal of our research funding is to provide initial funds, or additional funds, to explore blueberry health benefits.

The Council wants research to demonstrate benefits.  Of course it does.  These will be useful for marketing.

A priority for funding will be given to human clinical studies however the committee is also interested in further investigation of possible health benefits for pet or performance animals including dogs, cats and horses.

If the proposal is unlikely to demonstrate benefit, it won’t be funded.

That’s why I consider industry-funded research to be about marketing, not science.

Effect of Montmorency tart cherry juice on cognitive performance in older adults: a randomized controlled trial, Sheau C. Chai,, et al. Food Funct., 2019,10, 4423-4431.

Method: In this randomized controlled trial, 37 adults between the ages of 65–80 with normal cognitive function were recruited and randomly assigned to consume two cups of Montmorency tart cherry juice for 12 weeks.

Results: The within-group analysis showed that the visual sustained attention (p < 0.0001) and spatial working memory (p = 0.06) improved after the 12-week consumption of tart cherry juice compared with corresponding baseline values. Daily tart cherry juice consumption may improve cognitive abilities.

Conclusion: Our study demonstrated that daily intake of Montmorency tart cherry juice may help improve subjective memory and cognitive abilities in older adults as evidenced by increased contentment with memory, improved visual sustained attention and spatial working memory, and reduced movement time and total errors made on new learning tasks in older adults. T

Acknowledgements: The present study was supported by the Cherry Research Committee of the Cherry Marketing Institute, a non-profit organization. Tart cherry concentrates were provided by the Cherry Marketing Institute. Funders had no role in the study design, data collection, data analysis or interpretation, or writing of the manuscript.

Comment: I love cherries—a joy of summer—and wouldn’t it be wonderful if eating them was all you had to do to prevent cognitive decline.  Are cherries better than any other fruit or vegetable for this purpose?  This study did not examine that question but eating a healthy diet is always a good idea.  As for funders having no role, they don’t have to.  The mere fact that they funded this study skews the research question, as much evidence demonstrates (I reviewed this evidence in Unsavory Truth).