by Marion Nestle

Search results: research bias

Mar 13 2018

Unsavory Truth: How Food Companies Skew the Science of What We Eat

For review copies, interviews, etc, contact Kelsey Odorczyk at Basic Books: Kelsey.Odorczyk@hbgusa.com

For information about the book, see Basic Books/Hachette,  IndieBound,  Amazon

For reviews and media accounts, scroll down.

Portuguese translation, Elefante Editora, 2019:

Summary

Is chocolate heart-healthy? Does yogurt prevent type 2 diabetes? Do pomegranates help cheat death? News headlines bombard us with such amazing claims. They are reported as science, and have dramatic effects on what we eat.  Yet, as food expert Marion Nestle explains, these studies are more about marketing than science; they are often paid for by the companies and trade associations that sell those foods. Whether it’s a Coca-Cola-backed study hailing light exercise as a calorie neutralizer, claims for beef as a health food, or a report from investigators paid by a blueberry trade group concluding that this fruit prevents erectile dysfunction, every corner of the food industry knows how to turn conflicted research into big profit. As Nestle argues, it’s time to put public health first. Written with unmatched rigor and insight, Unsavory Truth reveals how the food industry manipulates nutrition science—and suggests what we can do about it.

Blurbs

“What happens when one of the country’s great nutrition investigators follows the money in food and science? You get this riveting, provocatively-written book, which deftly explores how the processed food industry has deepened our dependence on its products by sponsoring and manipulating food research for decades. This book should be read by anyone who has been seduced by the words, ‘New study shows…’—which is all of us.”  —Michael Moss, author of Salt Sugar Fat

“Marion Nestle is a tireless warrior for public health, and her meticulous research and irrefutable arguments are desperately needed right now. This book, as frightening as it is, compels us to discover where true health begins: nutrition starts in the ground, with real food that is sustainably grown, eaten in season, and alive.”  —Alice Waters, founder, owner, and executive chef of Chez Panisse

 “In clear, concise language, Marion Nestle details the many ways our ideas about what to eat are being manipulated by Big Food.  If you want to make better choices, read this book.”  —Ruth Reichl, former editor of Gourmet Magazine

 “Marion Nestle is a national treasure.  She has the courage to take on multinational corporations and the wisdom to separate the facts from the spin.  If you care about our food system and the health of your family, Unsavory Truth is essential reading.”  —Eric Schlosser, author of Fast Food Nation

“Marion Nestle has been a guiding light for sanity, credibility, and justice in food and nutrition for decades; she stands alone in her field. In Unsavory Truth, she exposes the awful deceptions practiced on eaters by manipulative food companies using ‘scientific research’ try to make themselves look good.”  —Mark Bittman, author of How to Cook Everything

 “Marion Nestle is a truth-teller in a world awash with nutrition lies of one kind and another. In this scintillating and eye-opening book, Nestle reveals how much of our confusion about food in modern times has been spread by the food industry itself, which passes off marketing as science and funds ‘research’ designed to show that its products are harmless. Unsavory Truth is essential reading for anyone in search of hard facts about what to eat.”  —Bee Wilson, author of First Bite and Consider the Fork

Reviews and media

2021

July 7   SPINS: What We’re Reading

2019

June 6  Review in American Journal of Public Health 2019;109(7):952-953.

Mar 11  Interview with VegSource with Jeff Nelson

Mar 5  TVO (Canada) The Agenda with Steve Paikin: Battling bias in nutrition research.  Also on YouTube.

Feb 17 Cover story based on Unsavory Truth, San Francisco Chronicle: “The myth-making of food

Feb 5  KQED San Francisco, Michael Krasny’s Forum

Feb 2  Sarah Boseley reviews Unsavory Truth in The Lancet

Jan/Feb  Nutrition Action Healthletter: Peter Lurie’s editorial

Jan 25  Interview with Holly Friend of LS:N Global

Jan 22  KPFK radio interview , Feminist Magazine with Lynn Harris Ballen

Jan 21  Cookery by the Book, podcast with Suzy Chase

Jan 16  Kara Goldin’s podcast on Unstoppable, Unsavory Truth

2018

Dec 21 The Hagstrom Report’s five best ag books of 2018

Dec 19  Podcast with Max Lugavere, The Genius Life Episode 39 (iTunes), on Unsavory Truth

Dec 17  Radio interview with Rose Aguilar, KALW San Francisco on Unsavory Truth

Dec 14 Podcast review by Narsai David, KCBS

Dec 13  Lecture on Unsavory Truth (video) at Hunter College NYC Food Policy Center

Dec 13  Online interview at PLoS Blog

Dec 12  Podcast with Wooden Teeth

Dec 6  NYU Journalism Kavli Conversation on Science Communication with Paul Greenberg, moderated by Robert Lee Hotz

Dec 3  Interview (podcast) with Bhavani Jaroff of iEat Green

Nov 30  Conor Purcell interview for Undark’s Five Questions

Nov 29 Paul Thacker on Unsavory Truth in the BMJ

Nov 28  Podcast interview with Monica Eng on Unsavory Truth: Chewing episode 55

Nov 26  Lisa Held on Unsavory Truth, Edible Manhattan

Nov 19  Interview with Gabrielle Lipton, Landscape News

Nov 18  Video of interview with Dean Malcolm Clemens, Forum at Grace Cathedral, San Francisco (audio file).

Nov 15  Review by Gavin Wren, Medium.com

Nov 15  Video of keynote at launch of UCSF Food Industry Documents Library (my talk is in Part I: 14:30)

Nov 12  Jennifer Bowden on Unsavory Truth in New Zealand’s The Listener.

Nov 12  Interview with Jesse Mulligan, Radio New Zealand

Nov 10  Review in New Scientist

Nov 7  Podcast interview with The Potter Report

Nov 7  A. Pawlowski.  What are superfoods?  The truth about blueberries, dark chocolate and pomegranate.  Today.

Nov 6  Interview with Paul Thacker.  Tonic.

Nov 4  Lorin Fries.  Who decides what you eat?  (Hint: it’s not only you).  Forbes.

Nov 1  Review in New York Journal of Books

Oct 31 Review from New York Magazine’s The Cut

Oct 31  Interview with Julia Belluz in Vox

Oct 30  Excerpt from Unsavory Truth on Medium.com: “When Big Soda Started Stalking Me”

Oct 30  NPR radio interview with Brian Lehrer

Oct 30 Yoni Freedhoff, Weighty Matters.

Oct 30  Jane Brody.  Confused by nutrition research?  New York Times, Science section.

Oct 29  RT America video interview on Boom Bust about Unsavory Truth.

Oct 28  Hailey Eber. How the food industry fooled us into eating junk.  New York Post, 42-43.

Oct 23  Nestle M.  Superfoods are a marketing ploy (excerpt).  The Atlantic .

Oct 22  Àlex Pérez.  Una verdad desagradable no vende.  ElPiscolabis (Spain).

Oct 18 Nature Magazine (2018;562:334-335): Felicity Lawrence reviews Deborah Blum’s The Poison Squad and Unsavory Truth as “Poisoned Platefuls.”  “Nestle…could make a fair claim to [Harvey] Wiley’s mantle today…The book is a remorseless dissection of the corruption of science by industry.”

Oct 18  Interview with Maggie Tauranac on Unsavory Truth, FoodPrint

Oct 16 Podcast with Danielle Nierenberg on Unsavory Truth and other matters

Oct 2  Science Magazine: “There is indeed something rotten in the state of dietary science, but books like this show us that we consumers also hold a great deal of power.”

Sept 25 La Stampa (Italy): “I cibi di lunga vita sono illusori e troppi sponsor li promuovono.” (The newspaper clip).

Sept 24  Publishers Weekly: ” a groundbreaking look at how food corporations influence nutrition research and public policy.”

Aug 13 Booklist: “This well-documented, accessible venture makes a compelling argument.”

Aug 1  Kirkus: “Nestle proves yet again that she is a unique, valuable voice for engaged food consumers.”

July 17  Phil Lempert’s Lempert Report: Get ready for a new era of transparency (video)

July 9  David Wineberg, “Nutrition: conflict of interest as a career,” Medium.com.

Feb 12 Finnish Public Radio interview about Unsavory Truth (Google Translate, English)

Jan 31 Profile in New Scientist: The Unpalatable Truth about Your Favorite foods

Tweets (Highly Selected)

Michael Pollan, October 30

Ing Fei Chen, October 16:  Undark

Yoni Freedhoff, October 7: his mentions

Basic Books, October 2: Mark Bittman blurb

Basic Books, September 25: Ruth Reichl blurb

Basic Books, September 6: Eric Schlosser blurb

Basic Books, August 28: Alice Waters blurb

Michael Pollan, August 18: “This is a terrific and eye-opening book”

Bee Wilson, August 17: “I feel lucky to have an advance copy …A great piece of investigative writing.”

Basic Books, August 17: Bee Wilson blurb

Dec 14 2017

Splenda is safe. Guess who funded the study.

For months now, I haven’t posted an industry-funded studies with results favorable to the sponsor, but this one about deserves mention.

Title: Critical review of the current literature on the safety of sucralose, by BA Magnuson, A Roberts, and ER Nestmann.

Journal: Food and Chemical Toxicology 2017:106:324-355.

Conclusion: “Collectively, critical review of the extensive database of research demonstrates that sucralose is safe for its intended use as a non-caloric sugar alternative.

Financial support was provided by the Calorie Control Council, Atlanta GA, to the employers of the authors for the preparation and publication of this review.

My comment: This lengthy review of literature on the safety of sucralose (Splenda) was commissioned by the Calorie Control Council, a trade association representing “manufacturers and suppliers of low- and reduced-calorie foods and beverages, including manufacturers and suppliers of more than two dozen different alternative sweeteners, fibers and other low-calorie, dietary ingredients.”

It paid authors affiliated with Health Science Consultants, Inc and Intertek Scientific and Regulatory Consultancy to produce this review.

  • The Calorie Control Council has a vested interest in demonstrating Splenda to be safe.
  • The consultant groups have a vested interest in pleasing the Calorie Control Council.
  • Therefore, this review has a higher-than-average likelihood of bias.

Is Splenda safe?  It very well may be safe, but some contrary evidence exists (this paper dismisses it).  It would be interesting to see how independent scientists view the matter.

Sep 19 2017

The NY Times’ blockbuster investigation: Big Food in Brazil

The article, which starts on the front page and continues to another two full pages and more, is headlined How Big Business got Brazil Hooked on Junk Food.

It’s mostly about how Nestlé (no relation) recruits women in low-income countries to sell the company’s products from small mobile carts.

Here are a few quotes:

  • Nestlé’s direct-sales army in Brazil is part of a broader transformation of the food system that is delivering Western-style processed food and sugary drinks to the most isolated pockets of Latin America, Africa and Asia. As their growth slows in the wealthiest countries, multinational food companies like Nestlé, PepsiCo and General Mills have been aggressively expanding their presence in developing nations, unleashing a marketing juggernaut that is upending traditional diets from Brazil to Ghana to India.
  • Sean Westcott, head of food research and development at Nestlé, conceded obesity has been an unexpected side effect of making inexpensive processed food more widely available.  “We didn’t expect what the impact would be,” he said.
  • Ahmet Bozer, president of Coca-Cola International, described to investors in 2014.  “Half of the world’s population has not had a coke in the last 30 days.  There’s 600 million teenagers who have not had a coke in the last week. So the opportunity for that is huge.”
  • “What we have is a war between two food systems, a traditional diet of real food once produced by the farmers around you and the producers of ultra-processed food designed to be over-consumed and which in some cases are addictive,” said Carlos A. Monteiro, a professor of nutrition and public health at the University of São Paulo.  “It’s a war,” he said, “but one food system has disproportionately more power than the other.”
  • [From Felipe Barbosa, a  Nestlé supervisor:] “The essence of our program is to reach the poor,” Mr. Barbosa said. “What makes it work is the personal connection between the vendor and the customer.”
  • But of the 800 products that Nestlé says are available through its vendors, Mrs. da Silva says her customers are mostly interested in only about two dozen of them, virtually all sugar-sweetened items like Kit-Kats; Nestlé Greek Red Berry, a 3.5-ounce cup of yogurt with 17 grams of sugar; and Chandelle Pacoca, a peanut-flavored pudding in a container the same size as the yogurt that has 20 grams of sugar — nearly the entire World Health Organization’s recommended daily limit.

The article is worth the read.  Or see the 3-minute video for a quick summary.  It also comes with a nifty interactive map of world obesity.

Politico Pro Agriculture asked Nestlé for a comment (this may be behind a paywall):

A Nestlé spokesperson defended the company while acknowledging the deeper childhood obesity problems currently plaguing Brazil. “We are disappointed by the New York Times’ biased approach in this article, which we believe does not accurately reflect the breadth and reality of our product portfolio in the context of the public health issues impacting the people of Brazil,” the spokesperson said. “However, we do agree that the real and serious issues raised in the article should be discussed in a balanced and constructive way that focuses on practical solutions.”

Resources

Here’s the article en Español.

And here it is em Português.

Take a look at Center for Science in the Public Interest’s report on Carbonating the World, which covers much of the same territory for Coca-Cola.  In the meantime, subsequent articles in this series are promised for soft drinks and fast food.

 

Aug 2 2017

Should nutrition scientists take food-industry funding?

I am an advisor to the American Society of Nutrition’s Early Career Nutrition group and was asked to address this question for its spring/summer newsletter (my piece starts on page 9).  Here’s what I said:

As a newly appointed advisor to ASN’s Early Career Nutrition (ECN) group, I am pleased to be asked to explain why I do not think it a good idea for nutrition scientists, practitioners, and societies to be funded by food, beverage, and supplement companies (collectively, the food industry) for research that is in any way related to their products. If we do, we run the risk of appearing as if our interests are conflicted. More than that, we risk being conflicted—influenced to be less critical or silent about nutrition issues related to the donor’s products. There is no getting around it: whatever the reality of the relationship, taking money from a for-profit food company makes us appear to be supporters of whatever products the company sells.

I worry a lot that financial ties between food companies and ASN tarnish its reputation and ours. It troubles me when critics outside our profession view us as “on the take” and publish reports exposing ASN’s financial ties to companies that have a marketing stake in what we study or say about their products. When ASN meetings are sponsored by food companies, it makes these financial ties seem normal. ASN provides a platform for industry-sponsored sessions such as the one this year on the benefits of Stevia, but you can bet they don’t include speakers who might say anything critical. Sponsorship excludes that possibility.

Most of what we know about the effects of sponsorship comes from a very large body of research on funding by the cigarette, chemical, pharmaceutical, and medical device industries. The results of this research are remarkably consistent: they demonstrate that industry funding influences the design, interpretation, and outcome of research. Nutrition is late to this type of investigation, but several recent studies show that studies funded by the food industry almost invariably favor the interests of the sponsor. Publication bias against negative studies explains only a small part of these findings.

Industry funding of nutrition research is an important issue where there are diverse opinions. ASN is a welcoming place encouraging discussion from members with all perspectives on topics including this one. ASN members share a common unifying goal of advancing nutrition science to promote the public welfare. Working together we can and we will continue to disclose potential conflicts of interest and advance the field for the public benefit. Dr. Mary Ann Johnson, ASN President
Investigators who take such funding insist that it has no effect on the design, conduct, interpretation, or publication of their research. This insistence is consistent with another large body of research demonstrating that gifts have a profound influence on attitudes, behavior, and action–but that recipients are blind to these effects. The medical literature shows that even small gifts—pens and pads—are enough to influence prescription practices, and that larger gifts have even greater effects. But the influence occurs below the radar of critical thinking. It is unintentional, unconscious, and unrecognized.

What most troubles me is the lack of questioning of industry penetration into our societies and research. I think we should be raising questions about ASN’s involvement with companies whose profits might be affected by our opinions or research results. Should ASN have competed to manage the industry-funded Smart Choices program that ended up putting a seal of approval on Froot Loops? Does it make sense for ASN to endorse public policy statements promoting the benefits of processed foods or opposing “added sugars” on food labels? Is it reasonable for ASN to argue on social media that it is inappropriate to question industry funding of research? Must ECN sessions at the annual meeting really be funded by companies such as PepsiCo (last year) or Abbott Laboratories? These actions send the message that ASN is an arm of the food industry and that we uncritically support what it makes, sells, or does.

But let’s turn to a more immediate concern: research funding. As early investigators, you face intense pressures to bring in external grants to pay for your studies, overhead, and maybe even your salaries. Government funding for many areas of nutrition research is declining. These pressures are real. But just as real are the effects of industry funding on research.
From March 2015 to March 2016, I posted summaries of industry-funded studies on my blog. During that year, I collected 168 studies. Of these, 156 yielded results favoring the sponsor’s interests. I only could find 12 studies that did not. This was a casually collected convenience sample but it did allow one conclusion: it is easier to find industry-funded studies with positive results than those with negative results. Nevertheless, recent systematic studies come to the same conclusion. Studies funded by Coca-Cola, for example, are far more likely to conclude that its products have no effect on obesity or type 2 diabetes than do studies funded by government or foundations.

Because we are generally unconscious of the influence of financial ties, it is easy for us to deny the influence or argue that nonfinancial interests—preferences for hypotheses and desires for career advancement–are just as biasing. Yes they may be biasing, but all scientists have them. In contrast to financial ties to industry, it is not possible to eliminate nonfinancial biases and still do science.

I am often asked whether there is a way to take money from food companies and maintain intellectual independence and professional reputation. I regret that I cannot think of any viable way to do that. The ASN has appointed a “Truth” commission to examine this issue and I look forward to its report. In the meantime, I am hoping that you will give thought to the potential conflict of interest and reputational loss that you risk with food industry ties. You must figure out for yourself whether you think the risks are worth taking.

If you do decide to engage with industry, you will need to disclose it. Most journals now require authors to reveal who pays for their work, but even when done diligently, disclosure is not sufficient to alert readers to the extent to which industry funding influences research outcome and professional opinion. Yes, disclosure is uncomfortable, perhaps explaining why so many studies identify frequent lapses. It is likely to become more uncomfortable. In response to a petition from the Center for Science in the Public Interest (which I co-signed), the National Library of Medicine has announced that it will henceforth add funding disclosures and conflict-of-interest statements to PubMed abstracts.

It is only fair to tell you how I handle these issues. My disclosure statement says:

Dr. Nestle’s salary from NYU supports her research, manuscript preparation, Website, and blog at https://foodpolitics.com. She also earns royalties from books and honoraria from lectures to university and health professional groups about matters relevant to this topic.” I also on occasion speak to food industry groups. When I do, I accept reimbursements for travel expenses but ask that honoraria be donated to the NYU library’s food studies collection.

This policy, imperfect as it may be, is the best I can do. I ask only that you think seriously about these issues and figure out for yourself how best to deal with them. I am happy to discuss these matters and am most easily reached at marion.nestle@nyu.edu.

References

  • Nestle M. Food company sponsorship of nutrition research and professional activities: A conflict of interest? Public Health Nutrition 2001;4:1015-22.
  • Nestle M. Corporate funding of food and nutrition research: science or marketing? JAMA Internal Medicine 2016;176(1):13-4.
  • Krimsky S. Science in the Private Interest: Has the Lure of Profits Corrupted Medical Research. Rowman and Littlefield, 2004.
  • Lo B, Field MJ, eds. Conflict of Interest in Medical Research, Education, and Practice. Washington, DC: National Academies Press; 2009.
  • Simon M. Nutrition Scientists on the Take from Big Food. Eat Drink Politics and the Alliance for Natural Health, Jun 2015.
Jun 21 2017

GMO propaganda film: Food Evolution

I have asked repeatedly to have my short interview clip removed from this film.  The director refuses.  He believes his film is fair and balanced.  I do not.

I am often interviewed (see Media) and hardly ever quoted incorrectly or out of context.  This film is one of those rare exceptions.

In my 10-second clip, I say that I am unaware of convincing evidence that eating GM foods is unsafe—this is what I said, but it is hugely out of context.

Safety is the industry’s talking point.  In the view of the GMO industry and this film, if GMOs are safe, they ought to be fully acceptable and nothing else is relevant.

I disagree.  I think there are plenty of issues about GMOs in addition to safety that deserve thoughtful consideration:  monoculture; the effects of industrial agriculture on the environment and climate change; the possible carcinogenicity of glyphosate (Roundup); this herbicide’s well documented induction of weed resistance; and the how aggressively this industry protects its self-interest and attacks critics, as this film demonstrates.

Food Evolution focuses exclusively on the safety of GMOs; it dismisses environmental issues out of hand.  It extols the benefits of the virus-resistant Hawaiian papaya and African banana but says next to nothing about corn and soybean monoculture and the resulting weed resistance, and it denies the increase in use of toxic herbicides now needed to deal with resistant weeds.  It says nothing about how this industry spends fortunes on lobbying and in fighting labeling transparency.

Instead, this film hammers hard on three out-of-context points:

  1. GMOs are safe.
  2. Anyone who thinks otherwise is anti-science, ignorant, and stupid.
  3. Organic foods are bad and proponents of organic foods are deceitful.

Its biases are apparent throughout but the bias against organics is particularly striking.

For example, in arguing that proponents of organic agriculture are paid by the organic industry, the film refers to an article on the front page of  the New York Times.  But most of that article was about how the GMO industry recruits and pays academic researchers to front for it.  The film fails to mention that.

The obvious question: Who paid for this film?

The official answer: The Institute for Food Technologists (IFT).

IFT is a professional association for food scientists and technologists involved in the processed food industry.  I have been a member of it for years; its journal, Food Technology is useful for keeping up with what the food industry is doing.

I had no idea that IFT sponsored films, let alone one that must have been very expensive to produce (on location in Hawaii and Uganda, among other places.)

I can’t help but think Monsanto or the Biotechnology Innovation Organization must have given IFT a grant for this purpose, but IFT takes complete responsibility for commissioning the film (if you have any information about this, please let me know).

Food Evolution is opening in New York on Friday this week.  I view it as a slick piece of GMO industry propaganda.

If you want a thoughtful discussion of the real issues raised by food biotechnology, you will need to look elsewhere.

Full disclosure: half of my book Safe Food: The Politics of Food Safety deals with GMO issues.  These have not changed much since the book appeared in 2003 and in a revised edition in 2010.  The GMO industry’s defenses and attacks are much the same, just louder and more expensively produced.

Apr 11 2016

The strange story of my accepted but yet-to-be published commentary on a Disney-sponsored study gets stranger

Last week, StatNews.com revealed that the Walt Disney company tried to withdraw a research study it had funded because its University of Colorado authors, Jim Hill and John Peters, were behind the Global Energy Balance Network, the group funded by Coca-Cola to minimize the role of sugary drinks in obesity.

The headline: “Disney, fearing a scandal, tried to press journal to withdraw research paper.”

StatNews.com based the story on e-mails obtained from the University of Colorado by Gary Ruskin of US Right to Know through open records requests.

An e-mail from John Peters to a Disney representative says “could I ask you to look this [draft press release] over and edit as you see fit.”

But the authors’ conflict-of-interest disclosure statement says:

This work was supported by the Walt Disney Company and by the National Institutes of Health (grant no. DK48520). The Walt Disney Company and the National Institutes of Health had no role in the design, analysis, or writing of this article.

This may be strictly true, but the authors were asking Disney to approve their press release, which is not exactly “no role.”

Readers: does any of this sound familiar?  In February, I wrote a blog post about precisely this article for which I wrote an invited Commentary, accepted by the journal but not published.  I said:

The paper turned out to be by a group of authors, among them John Peters and Jim Hill, both members of the ill-fated Global Energy Balance Network, the subject of an investigation by the New York Times last August…I thought Disney’s sponsorship of this research and its withholding of critical baseline and sales data on kids’ meals that the company considered proprietary did indeed deserve comment, and wrote my piece accordingly.  Brian Wansink [the journal editor] soon accepted it for publication but to my surprise, gave it to Peters et al. for rebuttal.  They filed a lengthy response.  I was then given the opportunity to respond, and did so, briefly.

My Commentary—and the back-and-forth—were omitted (although they are online and will be published in a later issue, apparently).

Brian Wansink wrote colleagues who are editing the next issue of the journal that the back-and-forth debate over the article “was heated, and it also dragged on (because of Disney approvals) and – as we feared – it missed the deadline of our issue.”

This suggests that Disney had even more of an involvement, but when I asked Wansink if Disney approvals were responsible for his having dropped my Commentary, he said no, they just ran out of room.

We now know that Disney was more involved than disclosed.  How involved?  We dont know but perhaps other e-mails will surface to answer that question.

In their Rebuttal to my Commentary, Hill and Peters said

We were disappointed by Dr. Nestle’s assertion that Disney’s decision to not allow publication of kid’s park attendance numbers or raw kid’s meal sales numbers (because of their proprietary nature in the competitive business of theme parks) and the fact that Disney funded the study raises “red flags” about the veracity of the data presented…While we believe caution and transparency are always key ingredients when working with industry we also believe that solving the obesity problem will require finding a productive model for working together that can channel everyone’s energy toward finding solutions.  The Disney study is a good example of why partnering with industry can help move the field forward.

I am sorry I disappointed them, but I disagree.

The e-mails demonstrate even more forcefully that the Disney study is a good example of why partnering with industry should raise acres of red flags.

To repeat my response:

The response from Peters and Hill still fails to acknowledge the severity of the problems posed by Disney’s sponsorship of their research—the company’s failure to produce data essential for proper interpretation of study results, and the level to which sponsorship by food companies biases such interpretations.  At one point, Disney boasted of the results of this research, confirming its benefit to marketing goals.  The threat of industry sponsorship to research credibility has received considerable press attention in recent months, as must surely be known to these authors. [References one and two]. 

Because of Disney’s funding, the company must have thought it had the right to determine whether and how its funded study would be published.  And, as these e-mails reveal, therein lies the problem.

Mar 4 2016

Julia Belluz (Vox) on my collection of studies sponsored by food companies

Julia Belluz of Vox has just done a story on my collection of studies funded by food companies.  Here are a few excerpts.  For the entire article and its excellent illustrations, click on the link):

About a year ago, Marion Nestle finally got sick of the rotten state of nutrition science.

Everywhere she looked, she found glaring conflicts of interest. “Without any trouble, I could identify industry-funded nutrition studies by their titles,” says the New York University professor. “It was so obvious”…But Nestle is not the first to notice this problem. Many nutrition researchers have been complaining about conflict-of-interest problems in their field for some time now. Whereas other fields, like medicine, have been putting in place safeguards to protect against undue industry influence, the field of nutrition has lagged behind in this regard.  And other research backs up Nestle’s findings. Take this review of studies on sugary drinks. Independently funded studies tend to find a correlation between soda consumption and poor health outcomes. Studies funded by soda makers, by contrast, are less likely to find such correlations. Or take this investigation of 206 publications on the health effects of milk, soft drinks, and fruit juices. Studies that were funded by beverage companies were four to eight times more likely to come to favorable conclusions about the health effects of those beverages.

The reporter interviewed researchers who work in food and nutrition about all this.

They all acknowledged that she was tapping into a real problem, one that’s been difficult for their community to address.  So why are conflicts of interest allowed to persist in nutrition research?  One root cause is the need for funding. Right now nutrition science is relatively underfunded by government, leaving lots of space for food companies and industry groups to step in and sponsor research…Tradition also plays a role. “Nutrition science has always been close to producers,” Dutch nutrition researcher Martijn Katan told me. “There’s such a direct interest in the outcomes of research for producers”…And food companies have ample incentive to promote this research. Under Food and Drug Administration rules, any health claims that they want to make on their packaging has to be backed up by scientific research. So the food industry has a keen interest in funding research — and favorable research that their profits may depend on.

She quotes Martijn Katan:

In the long term,” Katan said, “the deepest harm being done is that it undermines the credibility of science. In the short term, it means some people will eat more butter or cheese than is good for them, and that it will take longer to get people off soda.”

Her conclusion:

None of the researchers I spoke to suggested we should abolish industry funding of food and nutrition studies. As Katan has written, these collaborations can lead to fruitful discoveries…Instead, they wanted to see more awareness about the problem, more scrutiny of industry-funded research, and organized efforts to control conflicts of interest. “It’s not the quality of the science that’s at issue,” Nestle explains. “The studies are carried out according to strong scientific principles. But the bias seems to come in around the research question that’s asked, the interpretation of the results, putting a positive spin on findings even when the results are neutral.” That’s not good for science or for public health.

Feb 23 2016

More industry-funded studies. The score: 135/12. Correction: 132/12.

Corrections, February 25:  Several readers have written in to comment that two of these papers do not actually appear to benefit the sponsors.  I have written their comments in red.  A reader also filed a correction to one of listings for February 18.  That brings the score down to 132/12.

It’s been 11 months since I started collecting studies funded by food companies with results favorable to the company’s marketing interests.  I’ve now found 135 such studies versus just 12 with results unfavorable.

When the year is up, I will do an overall interpretation of what this collection does and does not signify, but for the moment I will just state the obvious: it is easier to find industry-funded studies with favorable rather than unfavorable results.

Enjoy this week’s collection.

Latin American Study of Nutrition and Health (ELANS): rationale and study design. M. Fisberg, I. Kovalskys, G. Gómez, A. Rigotti, L. Y. Cortés, M. Herrera-Cuenca, M. C. Yépez, R. G. Pareja,Guajardo, I. Z. Zimberg, A. D. P. Chiavegatto Filho, M. Pratt, B. Koletzko, K. L. Tucker and the ELANS Study Group. BMC Public Health (2016) 16:93.  DOI 10.1186/s12889-016-2765-y.

  • Conclusion: This study will provide valuable information and a unique dataset regarding Latin America that will enable cross-country comparisons of nutritional statuses that focus on energy and macro- and micronutrient intakes, food patterns, and energy expenditure.
  • Funding: The ELANS study and authors were partially supported by a scientific grant from the Coca Cola Company and by different grants and support from the Instituto Pensi/Hospital Infantil Sabara, International Life Science Institute of Argentina, Universidad de Costa Rica, Pontificia Universidad Católica de Chile, Pontificia Universidad Javeriana, Universidad Central de Venezuela (CENDESUCV)/Fundación Bengoa, Universidad San Francisco de Quito, and Instituto de Investigación Nutricional de Peru. The funders had no role in study design, data collection and analysis, the decision to publish, or the preparation of this manuscript. KLT received consulting fees from the Coca Cola Company to participate. MF is member of the directory of Danone Institute International.
  • A reader writes: Coca-Cola undoubtedly hopes that this study will support their efforts to put the blame on lack of exercise. However, the present paper gives no data, and the design does not seem biased. I do not think this paper can support marketing of Coca-Cola.  My response: OK.  Let’s call this one neutral and delete it from the list.

Biofortified yellow cassava and vitamin A status of Kenyan children: a randomized contr.  Am J Clin Nutr 2016; 103:258-267 doi:10.3945/ajcn.114.100164

  • Conclusion: In our study population, consumption of yellow cassava led to modest gains in serum retinol concentration and a large increase in β-carotene concentration. It can be an efficacious, new approach to improve vitamin A status.
  • Funding: Supported by the European Union’s Seventh Framework Programme (FP7/2007-2013) under grant agreement 211484, conducted within the framework of INSTAPA Project. HarvestPlus provided financial support for biochemical analyses and supplies. Capsugel (Bornem, Belgium), Laboratory&Allied (Nairobi, Kenya), DSM Nutritional Products/Sight and Life (Basel, Switzerland), and Laboratorium Medisan (Heerenveen, Netherlands) provided financial and technical support in producing supplements…None of the authors reported a conflict of interest. The funders had no role in the design, implementation, analysis, or interpretation of the data.
  • A reader writes: This study came out somewhat favorably for yellow cassava (non-GMO) and thus for HarvestPlus, but HarvestPlus is a charity with no commercial interests. DSM company provided the carotene capsules for the positive control group, but the study shows you might as well eat cassava naturally high in carotene instead of capsules.  My response: This one is not industry-funded.  Delete from list.

Effects of Diet Composition and Insulin Resistance Status on Plasma Lipid Levels in a Weight Loss Intervention in Women.Tran Le, BA; Shirley W. Flatt, MS; Loki Natarajan, PhD; Bilge Pakiz, EdD; Elizabeth L. Quintana, MS, RD Dennis D. Heath, MS1; Brinda K. Rana, PhD; Cheryl L. Rock, PhD, RD.  J Am Heart Assoc.2016; 5: e002771.  Originally published January 25, 2016.  doi: 10.1161/JAHA.115.002771.

  • Conclusions Weight loss was similar across the diet groups, although insulin‐sensitive women lost more weight with a lower fat, higher carbohydrate diet versus a higher fat, lower carbohydrate diet. The walnut‐rich, higher fat diet resulted in the most favorable changes in lipid levels.
  • Funding: This study was supported by the NIH (CA155435) and the California Walnut Commission.

Regular Fat and Reduced Fat Dairy Products Show Similar Associations with Markers of Adolescent Cardiometabolic Health. Therese A. O’Sullivan, Alexandra P. Bremner, Trevor A. Mori, Lawrence J. Beilin, Charlotte Wilson, Katherine Hafekost, Gina L. Ambrosini, Rae Chi Huang and Wendy H. Oddy.   Nutrients 2016, 8(1), 22; doi:10.3390/nu8010022.

  • Conclusions: Although regular fat dairy was associated with a slightly better cholesterol profile in boys, overall, intakes of both regular fat and reduced fat dairy products were associated with similar cardiometabolic associations in adolescents.
  • Funding: Therese A. O’Sullivan received a grant from The Dairy Health and Nutrition Consortium Australia (DHNC-MetX06-2011) which provided funding for the analysis and write up of this study. No other authors declare a conflict of interest.

Concord grape juice, cognitive function, and driving performance: a 12-wk, placebo-controlled, randomized crossover trial in mothers of preteen children. Daniel J Lamport, Clare L Lawton, Natasha Merat, Hamish Jamson, Kyriaki Myrissa, Denise Hofman, Helen K Chadwick, Frits Quadt, JoLynne D Wightman, and Louise Dye. AJCN. First published ahead of print February 10, 2016 as doi: 10.3945/ajcn.115.114553.

  • Conclusions: Cognitive benefits associated with the long-term consumption of flavonoid-rich grape juice are not exclusive to adults with mild cognitive impairment. Moreover, these cognitive benefits are apparent in complex everyday tasks such as driving. Effects may persist beyond the cessation of flavonoid consumption….
  • Funding:  Supported by Welch Foods Inc…. JDW is an employee of Welch Foods Inc. None of the other authors reported a conflict of interest.
  • Comment: Welch sent out a press release: “New research by the University of Leeds in the UK suggests that drinking Concord grape juice daily can benefit certain aspects of memory and everyday tasks in people with stressful lifestyles – specifically working mothers.”  Yoni Freedhoff has additional comments on Weighty Matters:Welch’s Study Finds Grape Juice Makes You Smarter #NotTheOnion.