I first read about this in a daily newsletter I subscribe to, Bakery and Snacks:   The Doritos effect: How tartrazine turns tissues temporarily transparent. When a study draws parallels with H.G. Wells’ The Invisible Man, you know it’s bound to be captivating. Could this scientific leap bring us closer to achieving a real-life version of Harry Potter’s invisibility cloak?… Read more

An ingredient in Doritos — tartrazine or Yellow 5 — is helping scientists see through the skin of mice. While they can’t see through human skin (it’s thicker and less permeable), this could be helpful in the future for early skin cancer detection. Imagine if it could replace a mammogram? On the other hand, Doritos food coloring is a chemical that the scientists said might not be totally harmless. (And to think so many people are eating it?) Read the Popular Science article about it. It’s fantastic.

Popular Science: The dye in Doritos can make mice transparent.  ‘It’s not magic, but it’s still very powerful.’

Because of a counterintuitive fundamental physics principle [selective absorption and scattering of light], Tartrazine, also known as Yellow 5, can temporarily turn biological tissue transparent to the naked eye, as described in a study published September 5 in the journal Science. 

The Science study: Achieving optical transparency in live animals with absorbing molecules.  Science.  Vol 385, Issue 6713.  DOI: 10.1126/science.adm6869

We next sought to demonstrate the ability of absorbing molecules to achieve tissue transparency in the mouse abdomen. Specifically, when a tartrazine solution was topically applied to the abdominal skin of a live mouse under anesthesia and gently massaged on the skin (Fig. 1, G and H), the abdominal skin not only darkened in color but also became more transparent in the red window (fig. S8). This transparency effect can be readily visualized with the naked eye and does not require any specialized imaging equipment…The transparent abdomen allowed us to directly observe internal organs, including the liver, small intestine, cecum, and bladder (Fig. 1, I and J). Moreover, we could also discern their movements, such as peristalsis, as well as motions synchronized with the heartbeat and breathing (Movies 1 and 2). The achieved abdominal transparency can be reversed by rinsing and massaging the skin with water (fig. S8).

Tartrazine is FD&C  Yellow #5

Tartrazine is a synthetic food colorant classified as an azo dye. It is lemon yellow in color and water soluble. Tartrazine is approved for use as a food colorant in the EU, USA, Canada, and other parts of the world for use in food, cosmetics, and medications. Its use in foods includes dairy products, beverages, desserts, confectionary, spices, dressings, jellies and sauces…It is one of the most commonly used and best known food additives…Of the synthetic food dyes, tartrazine has been implicated most often as a cause of adverse reactions.

Here’s what CSPI says about it.

Yellow 5 can be found in many foods, including beverages, gelatin desserts, candy, and baked goods. It’s the second-most widely used coloring and sometimes causes allergy-like hypersensitivity reactions, primarily in aspirin-sensitive persons, and triggers hyperactivity in some children. It may be contaminated with such cancer-causing substances as benzidine and 4-aminobiphenyl (or chemicals that the body converts to those substances).

CSPI has filed a petition to

Ban the Use of Yellow 5 and Other Food Dyes, in the Interim to Require a Warning on Foods Containing These Dyes, to Correct the Information the Food and Drug Administration Gives to Consumers On the Impact of These Dyes on the Behavior of Some Children, and to Require Neurotoxicity Testing of New Food Additives and Food Colors.

And now here’s another reason not to use it, even though it doesn’t do this in people, apparently.  Our skin is too thick.

Addition

A reader points out that tartrazine is on the list of food dyes now banned in California.  Good idea.

Here’s how I learned about this one: Unilever, Nestlé and Coca-Cola villainised for government scientist ties.  Mondelēz International, Tate & Lyle, Pepsico and a host of other global food and drink manufacturing majors face fresh scrutiny over their links to government-advising scientists…. Read more

Villainized?  Isn’t this just business as usual?

Not exactly.  An analysis in the BMJ (formerly British Medical Journal) says UK government’s nutrition advisers are paid by world’s largest food companies(see BMJ 2024;386:q1909).

The authors examined declared links between members of SACN (The UK Government’s Scientific Advisory Committee on Nutrition) and the food and drinks industry.

:

The study found

More than half of the experts on the UK government’s advisory panel on nutrition have links to the food industry…Campaigners say that these conflicts of interests at the heart of policy making are detrimental to public health. Others say that they reflect the lack of funding for nutrition research and that removing experts with industry links from SACN would “diminish” its expertise..

Six members of SACN are members of the American Society for Nutrition, which is funded by Mars, Mondelez, Nestlé, PepsiCo, and the Sugar Association, among others…SACN’s current work includes reviewing the evidence over ultraprocessed foods, artificial sweeteners, and plant based food and drink…Experts including van Tulleken and Percival say that SACN did not do enough to present the case for tougher regulation on ultraprocessed foods.

Two readers, Tara Kenny and Martin Caraher, sent this one:  Plant-based diets–impacts of consumption of little or no animal-source foods on human health.  by Alice V. Stanton  ^{Front. Nutr., 17 September 2024. Volume 11 – 2024 | https://doi.org/10.3389/fnut.2024.1423925}

The paper argues for the benefits of meat-based diets:

The protections provided by plant-based diets against NCDs [non-communicable diseases] appear to be more strongly associated with reduced intakes of calories and salt, and increased intakes of fruit, vegetables, nuts and whole grains, rather than with reduced intakes of ASFs [animal-source foods]. Any possible absolute adverse effects of red and processed meat consumption on NCDs are very small and uncertain…dietary guidelines should advise moderating excessive consumption, rather than substantially limiting or excluding ASFs from the human diet.

The author’s conflict-of-interest statement:

Alice Stanton was a part-time employee of Devenish Nutrition (2017–2023); and currently owns stock in Devenish Nutrition, an agri-technology company specializing in sustainable food solutions.

Comment

My readers point out that the author’s financial conflicts of interest are understated.  Devinish Nutrition is, in fact, a family business.  The company states it is “an innovator in animal nutrition by providing a wide range of products and services.”  It was acquired this year by EASY BIO a South Korean animal nutrition company.

Both readers also point out that Alice Stanton has pro-meat ideological conflicts of interest, but these concern me much less.  Everyone who does research has beliefs and hypotheses they want to test.  But not everyone stands to benefit financially from the outcome of their research or opinion, which is why full disclosure is so necessary.

For some reason, this did not get sent out yesterday and I do not want you to miss it.  It’s a really important story.

PFAS, Per- and polyfluoroalkyl substances, are synthesized chemicals resistant to water, grease, and heat, ubiquitous in consumer products, and widely dispersed in nature and in our bodies.

Their health effects are alarming: they are endocrine disruptors with adverse effects on the immune system, liver, birth weight, cancer.

Now they turn up in farmland, poisoning soil as well as people.

The New York Times did an investigation: Something’s Poisoning America’s Land. Farmers Fear ‘Forever’ Chemicals.

Known as “forever chemicals” because of their longevity, these toxic contaminants are now being detected, sometimes at high levels, on farmland across the country, including in Texas, Maine, Michigan, New York and Tennessee. In some cases the chemicals are suspected of sickening or killing livestock and are turning up in produce. Farmers are beginning to fear for their own health.

PFAS got on soil because of their presence in sewage sludge used as fertilizer.

PFAS in farmland is yet another reason to choose organics.  The Organic Standards specifically forbid use of sewage sludge as fertilizer.

The EPA is finally taking action on PFAS.  Better late than never.

The Global Health Advocacy Incubator (GHAI) has issued this new report.  It’s well worth a look.

By now, soda taxes are well established to decrease consumption and raise revenues that can be used for social purposes.  As you might imagine, the soda industry does not like such taxes.  As the report explains,

Recently, Big Soda has adapted their [the cigarette industry’s] playbook and shifted their approach from outrightly opposing SB [sugary beverage] taxes to favoring weaker SB tax standards. This report highlights different actions and narratives employed by the industry and demonstrates how these strategies follow a global playbook, including:

1. Proposing weaker taxes tailored to favor industry interests at the risk of public health.

2. Threatening and challenging governments that have passed an SB tax.

3.  Delegitimizing evidence to distort perceptions about SB taxes.

4.  Stigmatizing SB taxes through economic arguments.

5.  Taking advantage of and using vulnerable populations and environmental concerns to avoid the SB tax.

Under Strategy #5, for example, the report provides this information:

The report offers advice about how to counter industry measures by “(1) protecting the tax design to ensure it will have an optimal public health outcome, (2) safeguarding the policy decision-making process from undue influence and (3) leveraging opportunities for civil society to defend SB taxes.

For example, to safeguard policy decisions, it advises:

Avoid participating in public-private partnerships, especially those claiming to mitigate the “economic damages” of the SB tax through false solutions. This is the entry point for corporations to take a seat at the policy-making table and meddle with the design and implementation of the tax.

Soda taxes are up for renewal in Berkeley and are under consideration in Santa Cruz.  Stay tuned.

The USDA has released its annual report on Household Food Security in the United States in 2023.

The news is not good.

What’s especially tragic is the reversal of the pandemic decline in food insecurity.

Pandemic income support and higher SNAP benefits did exactly what they were supposed to.  They reduced poverty.

Congress, in its infinite wisdom, stopped those benefits.

The results are entirely predictable.

These, alas, are political choices.

There’s an election coming up soon…

Resources

• Food Security in the U.S.  Food security means access by all people at all times to enough food for an active, healthy life.
• Food Security in the United States
• Household Food Security in the United States in 2023: An estimated 13.5 percent of households (18.0 million) were food insecure in 2023, meaning they had difficulty at some time during the year providing enough food for all their members because of a lack of resources.
• Statistical Supplement to Household Food Security in the United States in 2023: Statistics presented in the supplement are based on data collected in the Current Population Survey (CPS) Food Security Supplement conducted in December 2023.

Thanks to Hugh Joseph for this one: Running for the Ribeye.

Team Beef was created in 2009 by the national beef checkoff program, the marketing and research group that requires beef producers and importers to pay a $1-per-head on animals they market. The stated goal is to “promote beef’s health benefits and showcase people leading active and healthy lifestyles fueled by lean beef,” according to the Cattlemen’s Beef Board website. There are more than 20 teams across the country, each independently run by the respective state’s beef board.

…“Team Beef is a collection of runners and athletes … that believe in beef as a powerful protein to fuel their training and their everyday lives,” said Kentucky rancher Joe Lowe, in a promotional video that includes him cheersing his wife Cassie with beef jerky.

…Some states require that team members go through an online, self-guided course called Masters of Beef Advocacy that trains them on how to speak knowledgeably about environmental sustainability, beef nutrition, animal welfare, and beef safety.

Comment

This is a great way to advertise beef, to associate beef with sports, and to deflect attention from the role of beef production in climate change, antibiotic overuse, and pollution of soil, air, and water.  The checkoff program is a partnership with the USDA.  Extremist Republicans want to get rid of checkoff programs (see Project 2025 agenda).  So do I (politics does indeed make strange bedfellows).

Nutrition Advocacy in Public Interest is “A national think tank on nutrition” in India, “consisting of independent experts in epidemiology, human nutrition, community nutrition and paediatrics, medical education, administration, social work and management.”  This group is calling for regulation of unhealthy  ultra-processed foods. 

This new report gives examples of food product ads, (50 of them) by method of appeal along with what information is concealed.  One example:

Take a look.  These are fun.  It’s terrific to see this kind of analysis coming from India.