In the Brave New World we now live in, food technology has scored a big win.  Food Navigator has the story: How does a cultivated chicken cell line meet kosher standards?

In a world first, OU Kosher [The kosher certification division of the Orthodox Union] has determined that the chicken cell line of Israeli start-up SuperMeat meets kosher standards.

In another world first, the OU has recognised cultivated meat as kosher and meat.

How is this even possible?

The OU’s recognition comes after a series of halachic discussions (concerning Jewish religious laws) and scientific reviews. The latter focused on avian embryogenesis and stem cells, including the observation of the excision of embryonic stem cells from a fertilised chicken egg prior to the appearance of blood spots.

SuperMeat worked closely with the OU and eminent rabbis to identify the vital elements of the sourcing and process to make sure that it holds to the highest standards of Kashrut [dietary laws]….

SuperMeat obtains the stem cells from very early after fertilisation of the egg at a precise time before the emergence of blood spots eliminating the necessity for slaughter and ensuring there is no blood involved in the process….SuperMeat does not use FBS [fetal bovine serum] or any other animal components in its media or process.

In my book about pet food with Malden Nesheim, Feed Your Pet Right, we wrote a chapter on Kosher pet food (one of my favorites).

The kosher laws are based on biblical injunctions against eating two kinds of animals, those that do not ruminate and do not have completely cloven hooves (Leviticus 11:26), and young animals cooked in their mother’s milk (Deuteronomy 14:21).   Thus, they forbid such things as eating pork or mixing meat and dairy foods at the same meal.

The Passover celebration requires one additional restriction.   Jews are not allowed to have in the house or to consume any foods containing chametz—wheat, wheat starch, wheat gluten, barley, oats, oat fiber, and other grains—precisely the ingredients in many pet foods.

Given the multiple and not always identifiable sources of ingredients in pet foods, it is difficult to imagine how pet foods can conform to Jewish dietary laws at any time, let alone at Passover.

Can pet foods be kosher?  Is it acceptable to hold Passover seders for dogs and cats, as some do?  And must pet owners who observe Jewish dietary laws feed their animals according to such laws?  The answers are typically Talmudic: yes, and no.

Super Meat is not on the market yet.  But aren’t you relieved to know that when it is, the Orthodox Union has given its blessing to cell-cultured meat.

Brave New World indeed.

I was induced to watch all of this video because Chris MacAskill, whom I do not know personally but who quoted me a couple of times briefly in a previous show, starts out his investigations by displaying my book Food Politics.  

This is titled, “How Food Myths SPREAD: Fact Checking Dr David Diamond”

I don’t know Dr. Diamond either, but he has some unusual and quite strong opinions about nutrition, which MacAskill, a historian, demolishes one after another.

MacAskill checks references, demonstrates the flaws in statements taken out of context, and does so carefully, compellingly, and entertainingly.

This is really worth watching (and I do appreciate the shout outs).

The Examination, a brand-new news outlet, and the Washington Post jointly published a jaw-dropping article last week about dietitians paid by food and supplement companies to defend and promote their products on Instagram and TikTok.

Why jaw-dropping?  Two reasons: the media—videos, posts—embedded in the article (these are amazing to see), and the non-disclosure of payment.

As the World Health Organization raised questions this summer about the risks of a popular artificial sweetener, a new hashtag began spreading on the social media accounts of health professionals: #safetyofaspartame….What these dietitians didn’t make clear was that they were paid to post the videos by American Beverage, a trade and lobbying group representing Coca-Cola, PepsiCo and other companies….The food, beverage, and dietary supplement industries are paying dozens of registered dietitians that collectively have millions of social media followers to help sell products and deliver industry-friendly messages on Instagram and TikTok, according to an analysis by The Examination and The Washington Post.

Here’s just one example:

Registered dietitian Lindsay Pleskot, of Vancouver, British Columbia, has posted videos of herself eating ice cream and peanut butter cups while telling people that denying themselves sugary food will only make cravings worse….These and other posts were paid for by the Canadian Sugar Institute.

I missed posting these last week (oops).

Blueberries set the standard for industry-funded studies (I discussed the origins of blueberry-industry funding in my book, Unsavory Truth).  Blueberry producers are still at it.  Here are two examples.

I.  This one started with a press release sent to my email:

From: Blueberries <updates@blueberrycouncil.org>
Date: August 29, 2023 at 11:59:59 AM EDT
Subject: Study Alert: New Research Links Blueberries to Gut Health Benefits

A new study published in Nutrients suggests blueberries may hold benefits for those suffering from functional gastrointestinal disorders (FGID). In this study, FGID patients saw greater abdominal symptom relief and improved markers of well-being, quality of life, and life functioning after consuming freeze-dried blueberry powder for 6 weeks as compared to a placebo treatment.

The study: Wilder-Smith CH, Materna A, Olesen SS. Blueberries Improve Abdominal Symptoms, Well-Being and Functioning in Patients with Functional Gastrointestinal Disorders. Nutrients. 2023; 15(10):2396. https://doi.org/10.3390/nu15102396.

Conclusion: Blueberries relieved abdominal symptoms and improved general markers of well-being, quality of life, and life functioning more than placebo in patients with FGID. Consequently, the polyphenol and fiber components of blueberries exert broad beneficial effects separate from the sugars present in both treatments.

Funding: This research was funded by a grant from the US Highbush Blueberry Council.

Comment: Of course it was.

II.  I read about this one in ConscienHealth.

Burning Fat with Wild Blueberries in 11 Athletes

This is nearly perfect clickbait that is just about meaningless for an average person in real life. Researchers did a study of fat oxidation after consuming freeze-dried powder from wild blueberries. They found an increased oxidation rate associated with consuming that powder in the 11 aerobically trained males they studied. So the press office at Cal Poly Humboldt, where the researchers work, issued a release saying wild blueberries help with burning fat.  From there, twitter and health reporters take the next leap, writing headlines like “eating wild blueberries can help you lose weight.”

The study: Pilolla KD, Armendariz J, Burrus BM, Baston DS, McCarthy KA, Bloedon TK. Effects of Wild Blueberries on Fat Oxidation Rates in Aerobically Trained Males. Nutrients. 2023; 15(6):1339. https://doi.org/10.3390/nu15061339.

Conclusion: “Results indicate that WBs may increase the rate of FAT-ox during moderate-intensity activity in healthy, active males.”

Funding: “This research was funded by Cal Poly Humboldt’s Dean of Research.* Freeze-dried Wild blueberry powder was donated by the Wild Blueberry Association of North America (WBANA).“

Comment: I agree that simply providing product to be tested is not an earth-shaking conflict of interest, but because the powder came from the WBANA the ties seem closer.  In any case, the idea that blueberry powder—not nearly as delicious as the real thing—can have these kinds of effects should raise eyebrows from the get go.  Studies of the health effects of one sincle food always require critical thinking and more than a modicum of skepticism.

As for the asterisk*:  My son went to Humboldt State College (long before it was taken over by Cal Poly) so I was especially interested in this.

I want to end the week with this unusual example.

Yes, avocados are fruits (hint: fruits have seeds).

This story begins with an emailed ad from an avocado trade association to subscribers to Today’s Dietitian.

In the largest study of its kind, published in the Journal of the American Heart Association, researchers across multiple institutions looked at the impact of consuming one avocado per day on weight-related measures, markers of cardiometabolic risk and diet quality—insights you won’t want to miss.

If you click around to further discussion, you get this:

Daily avocado consumption led to reductions in total and LDL cholesterol and improved diet quality compared to the control group. The Avocado Nutrition Center supported this study, and although the findings from one study cannot be generalized to larger populations, this study supports a growing body of evidence that suggests consuming heart-healthy avocados is associated with better diet quality.

Let’s take a look:

• The study: Effect of Incorporating 1 Avocado Per Day Versus Habitual Diet on Visceral Adiposity: A Randomized Trial. J Am Heart Assoc. . 2022 Jul 19;11(14):e025657.  doi: 10.1161/JAHA.122.025657. Epub 2022 Jul 5.  Authors: Alice H Lichtenstein ¹, Penny M Kris-Etherton ², Kristina S Petersen ³, Nirupa R Matthan ¹, Samuel Barnes ⁴, Mara Z Vitolins ⁵, Zhaoping Li ⁶, Joan Sabaté ⁷, Sujatha Rajaram ⁷, Shilpy Chowdhury ⁴, Kristin M Davis ⁸, Jean Galluccio ¹, Cheryl H Gilhooly ¹, Richard S Legro ⁹, Jason Li ⁶, Laura Lovato ¹⁰, Letitia H Perdue ¹⁰, Gayle Petty ¹, Anna M Rasmussen ⁶, Gina Segovia-Siapco ⁷, Rawiwan Sirirat ⁷, April Sun ⁶, David M Reboussin ¹⁰
• Conclusions: “In conclusion, in this randomized controlled multicenter parallel trial, the addition of 1 avocado per day to the habitual diet for 6 months in individuals with visceral adiposity did not reduce VAT and had minimal effect on risk factors associated with cardiometabolic disorders.”
• Funding: This work was supported by the Avocado Nutrition Center.

Comment: I don’t usually include the names of authors of industry-funded studies because I don’t see the “funding effect” (a higher probability of positive results) as personal to individual investigators; I see it as systematic.  But I listed these authors because they produced something quite rare: an industry-funded study that did not find positive results.  And they said so explicitly, without hedging or trying to spin the results so they looked  more favorable.

The avocado marketers did the spinning.  This, alas, is yet another hazard of  doing studies funded by food trade associations with vested interests in research outcome.  Investigators have no control over how the sponsor will use or spin their research results, as we see in this example.

Addition, September 16

I often hear criticisms that I don’t deal with the science when I post industry-funded studies.  I don’t because how the science is conducted is rarely the problem.  Instead, industry influence turns up most frequently in the study design or in the interpretation of the results.  That’s what’s happening here, as a reader, mrpicasso2, writes:

Wow! This is astounding how the Avocado marketers try to spin the results in their favor. “Changes in most secondary and additional outcome measures (cardiometabolic risk factors), except for modest decreases in total cholesterol and LDL‐C concentrations, were not statistically significant” became “Daily avocado consumption led to reductions in total and LDL cholesterol and improved diet quality compared to the control group.”

And even the “improved diet quality” is a big stretch because the Healthy Eating Index (HEI) values (even when split into below and above the median subgroups) were not significantly different. It’s true the avocado arm values were numerically higher (0.064 vs 0.044, and 0.083 vs 0.069) but without reaching statistical significance they are indistinguishable.

Of course the Avocado marketers don’t mention that there were 9 adverse events in the Avocado diet arm compared with none in the habitual diet group.

This reminds me of the story of the boy who was so excited to get a pile of horse manure for his birthday because he reasoned that with so much manure there had to be a pony near by.

The study:  Martinez-Canton M, Galvan-Alvarez V, Garcia-Gonzalez E, Gallego-Selles A, Gelabert-Rebato M, Garcia-Perez G, Santana A, Lopez-Rios L, Vega-Morales T, Martin-Rincon M, et al. A Mango Leaf Extract (Zynamite^®) Combined with Quercetin Has Exercise-Mimetic Properties in Human Skeletal Muscle. Nutrients. 2023; 15(13):2848. https://doi.org/10.3390/nu15132848

Hypothesis:  Zynamite PX^®, a mango leaf extract combined with quercetin, enhances exercise performance by unknown molecular mechanisms.

Conclusion: Zynamite PX^® elicits muscle signaling changes in resting skeletal muscle resembling those described for exercise training and partly abrogates the stress kinases responses to exercise as observed in trained muscles.

Funding: This investigation was co-financed in part by Nektium Pharma S.L., Ministerio de Economía y Competitividad…Consejo Superior de Deportes de España (EXP_75097), FEDER and Cabildo de Gran Canaria…and FDCAN (Fondo de Desarrollo de Canarias).

Conflicts of Interest: The present investigation was partially financed by Nektium Pharma S.L, who provided the polyphenolic compounds and participated in the experimental design, although they were fully excluded from participation in experimental data collection, data analysis and interpretation of results. The remaining funding agencies had no role in study design, data collection, management, data analysis, interpretation of data, writing of the report, and the decision to submit the report for publication.

Comment: This is a classic example of an industry-funded supplement study with favorable interpreted favorably.  The manufacturer paid for the study as part of a private-public partnership to aid businesses in the Canary Islands.

For this one I thank Jerry Hagstrom, who writes The Hagstrom Report (Ag news as it happens) to which I subscribe.

This too begins with a press release: “REDISCOVER FIGS: THE ANCIENT FRUIT WITH MODERN APPEAL: Newly Published Literature Review Suggests the Intake of Figs Regularly in the Diet, Alone or with Other Dried Fruits, Increases Select Micronutrient Intake and is Associated with Higher Diet Quality.”

I am way behind on posting all the industry-funded studies sent to me and collected, so will share a week’s worth of fruit studies .  This is to emphasize the obvious point that fruit is good for you, but one is not necessarily better than another–except to its marketers.  Enjoy!

Here’s the first: strawberries.

I heard about this from two news releases, and because it was sent to me by Charles Platkin, Executive Director, Center for Food as Medicine  and Distinguished Lecturer at Hunter College, City University of New York.

• From CBS News, Boston:  “Strawberries could improve heart and brain health, researchers say.“
• From Neuroscience News: “Berry Good News: Daily Strawberries Boost Cognitive & Cardio Health.”

Wow.  This is exciting.  I had strawberries with my cereal for breakfast this morning.

I could not wait to read the study.

Uh oh.  Not yet published.  But given in a poster session at the American Society for Nutrition meetings in Boston last month.

• Title: The Impact of Strawberries on Cognition and Cardiovascular Health of Older Healthy Adults: A Randomized, Crossover, Double-Blind, Placebo-Controlled Clinical Trial .
• Objectives: The polyphenolic compounds in strawberries may improve cognitive function and cardiovascular health due to their antioxidant capacities. This study aimed to examine the effects of strawberries on cognitive function and cardiometabolic health in healthy aging adults.
• Methods:  This was a randomized, crossover, double-blind, placebo-controlled clinical trial with 35 healthy older adults  given 26 grams of freeze-dried strawberry powder (not strawberries) and a control powder daily for 8 weeks each.
• Results:  The strawberry powder group increased processing speed.  The control group increased episodic memory.  : The powder also had other effects: “Strawberry consumption reduced systolic blood pressure…Total antioxidant capacity significantly decreased during the control trial …and significantly increased with strawberry consumption.”
• Conclusions: This study demonstrates that daily consumption of 26 grams of freeze-dried strawberry powder moderately improves cognitive processing speed, lowers systolic blood pressure, and increases total-antioxidant capacity, potentially promoting cognitive function and improving cardiovascular risk factors.
• Funding Sources: This study was funded by California Strawberry Commission.

Comment: Of course it was.  Who else would care about the effects of strawberry powder.  Not that no other fruit powders were tested; I would expect all of them to produce similar effects, whatever those effects might be.  Given that the control group performed better on memory tests, you could interpret the results as not particularly meaningful.  But one characteristic of industry funded studies is to put a positive spin on whatever results occur.  We can argue about the methods when the study is actually published.  In the meantime, we have press releases.

Oh.  And my morning strawberries were somewhat local, red all the way through, and tasted like strawberries.  Do I feel smarter as a result?  Sure, why not.